Ibudilast-d3 azole D3 Chemical Name: (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-hydroxypropanamido]acetyl}pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-4-methylpentanamido]-4-carbamoylbutanamido]acetamido}-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-methylpentanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S

Chemical Name: (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-hydroxypropanamido]acetyl}pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-4-methylpentanamido]-4-carbamoylbutanamido]acetamido}-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-methylpentanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1S

ClH/c17-16(18

Smiles: [2H]C([2H])([2H])C(CCC[C@@H](C)[C@H]1CC[C@H]2/C(/CCC[C@@]21C)=C/C=C1/C[C@@H](O)CCC/1=C)C([2H])([2H])[2H]

760nM(HDAC2)Target: HDAC in vitro: Pimelic Diphenylamide 106 has preference toward HDAC3 with Ki of 14 nM

InChiKey: LZPQCDPVLUEOSL-UHFFFAOYSA-N

Ibudilast-d3 azole D3 Chemical Name: (2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-[(2S)-2-{2-[(2S)-2-[(2S)-2-(2-{[(2S)-1-[(2S)-1-{2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-hydroxypropanamido]acetyl}pyrrolidine-2-carbonyl]pyrrolidin-2-yl]formamido}acetamido)-4-methylpentanamido]-4-carbamoylbutanamido]acetamido}-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-carbamoylbutanamido]-5-carbamimidamidopentanamido]-4-methylpentanamido]-4-methylpentanamido]-N-[(1S)-1-{[(1S)-1-[({[(1S)-2-carbamoyl-1-{[(1S)-1-{[(1S)-1-{[(1S)-1-[({[(1SIbudilast d3 (KC 404 d3) is the deuterium labeled Ibudilast. Ibudilast (KC 404) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti dementia agent counteracting neurotoxicity in activated microglia. Product information CAS Number: 102064