PF-06733804 DT oxalate Smiles: CC1(C)[C@H](CC[C@]2(C)[C@@H]1CC=C1C2=CC[C@]2(C)[C@H]3C[C@](C)(CC[C@@]3(C)CC[C@]21C)COC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1

Smiles: CC1(C)[C@H](CC[C@]2(C)[C@@H]1CC=C1C2=CC[C@]2(C)[C@H]3C[C@](C)(CC[C@@]3(C)CC[C@]21C)COC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1

54)55)23-17-24(38(49)43-28-3-11-34(12-4-28)66(56

56 μg/mL in the DPPH assay

L-Homocysteine induces upregulation of cathepsin V that mediates vascular endothelial inflammation in hyperhomocysteinaemia

InChiKey: ZZORFUFYDOWNEF-WFGJKAKNSA-N

PF-06733804 DT oxalate Smiles: CC1(C)[C@H](CC[C@]2(C)[C@@H]1CC=C1C2=CC[C@]2(C)[C@H]3C[C@](C)(CC[C@@]3(C)CC[C@]21C)COC(=O)C1=CC=CC=C1)OC(=O)C1=CC=CC=C1PF 06733804 is a potent pan Trk inhibitor in cell based assays with IC50s of 8. 4 nM, 6. 2 nM and 2. 2 nM for TrkA, TrkB and TrkC, respectively. Anti hyperalgesic effect. Product information CAS Number: 1873373 33 1 Molecular Weight: 474. 38 Formula: C20H19F5N4O4 Chemical Name: 6 amino 5 {[(3S) 4,4 difluoro 1 {2 [4 (trifluoromethoxy)phenyl]acetyl}pyrrolidin 3 yl]oxy} N methylpyridine 3 carboxamide Smiles: