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InChiKey: GRBKWAXRYIITKG-QFMFQGICSA-N
Formula: C5H8N6Na2O5S
65(1):61-9
is a potent and selective inhibitor of Bruton's tyrosine kinase (BTK)
17-pentaazacycloicosane-4-carboxamide acetate
TPT-260 dihydrochloride - CAS# 2076-91-7 llardiine InChiKey: GRBKWAXRYIITKG-QFMFQGICSA-NTPT 260 2HCl, also known as R55, is a thiophene thiourea derivative with molecule weight 260. 00 in free base form. There is no formal name yet, we temporally call this molecule as TPT 260. TPT260 acts as a chaperone to stabilize the retromer complex against thermal denaturation (Kd = ~ 5 M). In cultured hippocampal neurons, TPT 260 dose dependently increases the level of retromer proteins, redirects APP from the endosome, and reduces the formation of