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1159/000328773
Smiles: CC1=CC2=C(C=C1C)NC1C(NC(=O)NC1=O)N2C[C@H](O)[C@H](O)[C@H](O)CO
5-dihydroxy-6-(hydroxymethyl)-3-{[(2S
Azelastine (4 mg/kg
InChiKey: VOPDXHFYDJAYNS-UHFFFAOYSA-N
NMS-1286937 Catalog No.:M9125-10 1159/000328773Onvansertib, also know as NMS P937, PCM 075 and NMS1286937, is a n orally bioavailable, small molecule Polo like kinase 1 (PLK1) inhibitor with potential antineoplastic activity. Polo like kinase 1 inhibitor NMS 1286937 selectively inhibits PLK1, inducing selective G2 M cell cycle arrest followed by apoptosis in a variety of tumor cells while causing reversible cell cycle arrest at the G1 and G2 stages without apoptosis in normal cells. PLK1
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