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CNX-1351 - CAS# 1276105-89-5 Catalog No.:M9803-10 Ethamsylate reduces the mean bleeding

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Description

Ethamsylate reduces the mean bleeding time when administered systemically or orally to rabbits

Chemical Name: methyl4-(2-fluoro-3-(3-(6-methylpyridin-3-yl)ureido)benzyl)piperazine-1-carboxylate

is An orally bioavailable synthetic P2 threonine boronic acid inhibitor of the chymotrypsin-like activity of the proteasome

138 nM (γ-C1A)

2019 Feb 14

CNX-1351 - CAS# 1276105-89-5 Catalog No.:M9803-10 Ethamsylate reduces the mean bleedingCNX 1351 is a selective covalent Inhibitor of PI3K. In an end point assay, CNX 1351 potently inhibited PI3K and was 20400 times less potent against , , and . CNX 1351 inhibit PI3K signaling in cells and shows prolonged inhibition consistent with a covalent mechanism of Action. CNX 1351 inhibits growth of cells dependent on PI3K. CNX 1351 also inhibits PI3K signaling in vivo and bonds to p110. Product information CAS Number: 1276105 89 5 Molecular

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