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This agent also blocks the tyrosine kinase activity of epidermal growth factor receptor (EGFR)
Aguilar-Morante D
BTB06584 is an IF1 -dependent selective inhibitor of the mitochondrial F1 Fo-ATPase
MLN2238 is an N-capped dipeptidyl leucine boronic acid and preferentially bound to and inhibited the chymotrypsin-like proteolytic (β5) site of the 20S proteasome with an IC50 value of 3
InChiKey: JDQOICVJUDEXEQ-UHFFFAOYSA-N
Dxd 935 This agent also blocks theDxd (Exatecan derivative for ADC) is a potent DNA topoisomerase I inhibitor, with an IC50 of 0. 31 M, used as a conjugated drug of HER2 targeting ADC (DS 8201a). Product information CAS Number: 1599440 33 1 Molecular Weight: 493. 48 Formula: C26H24FN3O6 Synonym: Exatecan derivative for ADC Chemical Name: N [(10S, 23S) 10 ethyl 18 fluoro 10 hydroxy 19 methyl 5, 9 dioxo 8 oxa 4, 15 diazahexacyclo[14. 7. 1. 0, . 0, . 0, . 0, ]tetracosa 1, 6(11), 12, 14,
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