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Positive allosteric modulation of GABA-A receptors reduces capsaicin-induced primary and secondary hypersensitivity in rats
Chemical Name: (5E
Smiles: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@H]3[C@H](CC[C@@]21C)[C@@]1(C)CC[C@@H](O)C[C@H]1[C@@H](CC)[C@H]3O
CAS Number: 1420477-60-6
37)38/h2-5
A-1165442 Catalog No.:M18437-C Positive allosteric modulation of GABA-AA 1165442 is a potent, competitive and orally available TRPV1 antagonist with an IC50 of 9 nM for human TRPV1. Product information CAS Number: 1221443 94 2 Molecular Weight: 431. 86 Formula: C22H20ClF2N3O2 Chemical Name: 1 [(4R) 7 chloro 2,2 bis(fluoromethyl) 3,4 dihydro 2H 1 benzopyran 4 yl] 3 (3 methylisoquinolin 5 yl)urea Smiles: CC1=CC2C(=CC=CC=2C=N1)NC(=O)N[C@@H]1CC(CF)(CF)OC2=CC(Cl)=CC=C21 InChiKey: VJJGAJAUECQWSZ LJQANCHMSA N InChi: InChI=1S
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