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Similarly in the proliferation assay
dosing for 14 days with Palbociclib (150 or 75 mg/kg) produces rapid tumor regressions and a corresponding tumor growth delay of ~50 days with >1 log of tumor cell kill at the highest dose tested
Buhrlage SJ
PubMed PMID: 26075265
Domchek SM
AMD-3465 hexahydrobromide - CAS# 185991-07-5 60228 Similarly in the proliferation assayAMD 3465, CAS No. 185991 07 5, is a novel CXCR4 receptor antagonist with potential anticancer and anti HIV activity. AMD 3465 can block infection of T tropic, CXCR4 using HIV. Product information CAS Number: 185991 07 5 Molecular Weight: 896. 07 Formula: C24H44Br6N6 Synonym: AMD 3465 AMD3465 Chemical Name: N (4 ((1,4,8,11 tetraazacyclotetradecan 1 yl)methyl)benzyl) 1 (pyridin 2 yl)methanamine hexahydrobromide Smiles: Br. Br. Br. Br. Br. Br.
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