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H2O : 10 mg/mL (14
with a Kd of 79 nM
CI994 was administered to mice via oral gavage (PO) or intraperitoneal injection (IP) at 5-35 mg/kg once per day
Juan-Garcia A
COC(=O)C1=CC(=CC(CN2CCN(CC2)C(N)=N)=C1)C(=O)N1CCN(CC1)C(=O)C1C=CC(=CC=1)C(N)=N
Ponesimod bersonine hydrochloride H2O : 10 mg/mL (14Ponesimod (ACT 128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1 mediated signal transduction with high potency (EC50=5. 7 nM). Ponesimod can protect against lymphocyte mediated tissue inflammation. Product information CAS Number: 854107 55 4 Molecular Weight: 460. 97 Formula: C23H25ClN2O4S Chemical Name: (2E,5Z) 5 ({3 chloro 4 [(2S) 2,3
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