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Chemical Name: N-(3-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3
CAS Number: 55721-31-8
VX-765 has shown activity in preclinical models of chronic epilepsy
PMID: 31666698
Chemical Name: 2-Amino-4-(4-fluoronaphth-1-yl)-6-isopropylpyrimidine
VCP 171 KKε-IN-1(compound 1) Chemical Name: N-(3-((2-((4-(4-methylpiperazin-1-yl)phenyl)amino)thieno[3Adenosine A1 receptor positive allosteric modulator (PAM) (pKB = 5. 65, binding cooperativity with NECA 0. 68). In absence of orthosteric agonist, VCP171 behaves as an allosteric partial agonist, inhibiting cAMP activity. Inhibits AMPA receptor mediated evoked excitatory postsynaptic current (eEPSC) amplitude in lamina I and II neurons in a rat partial nerve injury model of neuropathic pain. Product information CAS Number: 1018830 99 3 Molecular
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