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Elabela(19-32) mino]-1 3-dihydro-2H-imidazo[4 5-b]pyridin-2-one-d4 63)64)18-36(32)84(74

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Description

63)64)18-36(32)84(74

12 days) significantly enhances the inhibitory effect of carboplatin on A549 cells at 50 mg/kg

Smiles: CC(C)C[C@H](NC(=O)[C@@H](NC(=O)[C@H](CC1=CNC2=CC=CC=C12)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CCCCN)NC(=O)CNC(=O)[C@@H]1CCC(=O)N1)[C@@H](C)CC)C(O)=O

CAS Number: 202645-74-7

and KB (nasopharyngeal carcinoma)

Elabela(19-32) mino]-1 3-dihydro-2H-imidazo[4 5-b]pyridin-2-one-d4 63)64)18-36(32)84(74Elabela(19 32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19 32) activates the Gi1 and arrestin 2 signaling pathways with EC50s of 8. 6 nM and 166 nM. Elabela(19 32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart. Product information CAS Number: 1886973 05 2 Molecular Weight: 1707. 03 Formula: C75H119N25O17S2 Chemical Name: (2S) 1 [(2S) 2 {[(2S) 1

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