NVS-ZP7-4 Size:10mg solid with IC50 ranging from 282

with IC50 ranging from 282 nM for Src to >20 μM for Cdk4

7 macrophages in vitro at a dosage of 10μM

Formula: C19H19ClN4O3

Lomitapide mesylate

Preclinical testing confirmed promising antiproliferative activity

NVS-ZP7-4 Size:10mg solid with IC50 ranging from 282NVS ZP7 4 is a Zinc transporter SLC39A7 (ZIP7) inhibitor that is also the first reported chemical tool to probe the impact of modulating ER zinc levels and investigate ZIP7 as a novel druggable node in the Notch pathway. Product information CAS Number: 2349367 89 9 Molecular Weight: 501. 62 Formula: C28H28FN5OS Chemical Name: 1 [(2S) 2 [(6 fluoro 1,3 benzothiazol 2 yl)amino] 3 phenylpropyl] 2',3' dihydro 1'H spiro[piperidine 4,4' quinazolin] 2' one