Human IL10 Package Size:1mg The encoded protein is known

The encoded protein is known to regulate the condensation of heterochromatin in response to DNA damage and play a role in repressing transcription

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010 EU per 1 ug of the protein by the LAL method Activity Measured by its ability to inhibit BMP-4-induced alkaline phosphatase production by ATDC5 mouse chondrogenic cells The EC50 for this effect is 12-20 ng/mL in the presence of 50 ng/mL of Recombinant Human BMP-4

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Human IL10 Package Size:1mg The encoded protein is knownBcakground Interleukin 10 ,also known as cytokine synthesis inhibitory factor (CSIF), is the charter member of the IL 10 family of alpha helical cytokines that also includesIL 19, IL 20, IL 22, IL 24, and IL 26 AK155 (1, 2). IL 10 is secreted by many activated hematopoietic cell types as well as hepatic stellate cells, keratinocytes, and placental cytotrophoblasts (2 5). Mature human IL 10 shares 72% 86% amino acid sequence identity with bovine,