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binds and stabilizes single-stranded DNA intermediates
The isoforms lacking the transmembrane domain may negatively regulate the apoptosis mediated by the full length isoform
Mutations in this gene are associated with Smith-Kingsmore syndrome and somatic focal cortical dysplasia type II
• For automated runs: perform UV sterilization of the instrument for at least 15 min and clean internal walls with 75% alcohol wipes before and after runs
which in turn phosphorylate to activate the serine/threonine specific protein kinases
PAK1/PAK2/PAK3 (phospho-Ser144/Ser141/Ser154) rabbit monoclonal antibody Pipette Controllers binds and stabilizes single-stranded DNASpecification Full name PAK1 PAK2 PAK3 (phospho Ser144 Ser141 Ser154) rabbit monoclonal antibody Alternative names 50 l 100 l Reactivity rabbit monoclonal Applications WB, IF Host Rabbit Clone type rabbit monoclonal Target Background The PAK1 gene encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and