If the target creature is an illegal target as Sin's last ability tries to resolve, it won't resolve and none of its effects will happen
You can even sculpt combat to have a bigger creature die with Rimrock Knight giving +2/+0 to a key creature destined to die in combat
(Bevy of Beebles) Bad Ass Baron Von Count Bat- Beast in Show Bee-Bee Gun Better Than One Big Boa Constrictor Blacker Lotus Blast from the Past Bloodletter Blurry Beeble Boomflinger Boomstacker Booster Tutor Border Guardian Bosom Buddy Box of Free-Range Goblins Bronze Calendar Brushstroke Paintermage Bumbling Pangolin Bureaucracy Burning Cinder Fury of Crimson Chaos Fire Bursting Beebles Buzz Buggy Buzzing Whack-a-Doodle By Gnome Means Cardboard Carapace Cardpecker Carnivorous Death-Parrot Censorship Chaos Confetti Charm School Cheap Ass Cheatyface Checks and Balances Chicken Egg Chicken la King Chipper Chopper Chittering Doom Chivalrous Chevalier Circle of Protection: Art City of Ass Clam Session Clam-I-Am
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There are a number of cards you can't use in Explorer: Expressive Iteration Field of the Dead Geological Appraiser Karn, the Great Creator Kethis, the Hidden Hand Leyline of Abundance Lurrus of the Dream-Den Nexus of Fate Oko, Thief of Crowns Once Upon a Time Teferi, Time Raveler Tibalt's Trickery Underworld Breach Uro, Titan of Nature's Wrath Veil of Summer Wilderness Reclamation Winota, Joiner of Forces MTG Alchemy banlist Alchemy is another digital format for MTG Arena, which is based on the Standard card pool
Esper Sentinel An astonishingly good card draw spell for White, Esper Sentinel works brilliantly in Commander