CB1-IN-1 Catalog No.:M21313-C 19-decaen-2-yl]acetamido}butanedioate

19-decaen-2-yl]acetamido}butanedioate

4R)-2-[(4R)-2-[2-(acetyloxy)-6-pentylphenyl]-4

Smiles: COC1C=CC(=CC=1)C(OC[C@H]1O[C@H]([C@H](F)[C@@H]1O)N1C=NC2C1=NC=NC=2NC(=O)C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC(=CC=1)OC

the drug does not need hepatic activation

Smiles: NCCOCCOC1=CC=CC2=C1C(=O)N(C1CCC(=O)NC1=O)C2=O

CB1-IN-1 Catalog No.:M21313-C 19-decaen-2-yl]acetamido}butanedioateCB1 IN 1 (BPRCB1184) is a peripherally restricted CB1R antagonist, with Ki of 0. 3 nM and 21 nM for CB1R (EC50 = 3 nM) and CB2R, respectively. IC50 value: 0. 3 nM (Ki, CB1R) 21 nM (Ki, CB2R)Target: CB1Rin vivo: CB1 IN 1 is a novel peripherally restricted cannabinoid 1 receptor antagonist with significant weight loss efficacy in diet induced obese mice. CB1 IN 1 has great potential to ameliorate this related metabolic syndrome. Product information CAS