The tradeoff is that you dont get a trigger for mutating like all the others, but the stats look good for a defensive creature that generates cheap advantage every turn its alive
For example, if the four players in your game reveal 4, 7, 7, and 7, Wheel of Misfortune will deal 7 damage to each of the last three players and those three players will discard their hand and draw seven cards.
Endurance, as part of the pitch cards and evoke cycle of Modern Horizons 2, has multiple reasons whats making it extremely good
It will lose all of its previous card types and subtypes, but it will keep any supertypes (such as legendary) it previously had
This cycle is functional, but not a top choice if you have access to better alternatives