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12 hours) shows near complete AR degradation (>98%) in prostate cancer cells
7-tetrahydrothieno[3
Molecular Weight: 409
Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells
individual plaques could be distinguished within 30 to 60 min after a single IV injection or a single IP injection of Methoxy-X04
PHT-427 Size:2mg solid 12 hours) shows near completePHT 427 is an AKT inhibitor that inhibits AKT and PDPK1 at low micromolar concentrations in numerous cancer cell lines and exhibits good oral anti tumor activity in mouse xenograft models. PHT 427 reduces the phosphorylation of AKT and PDPK1. Following the administration of a single oral dose of PHT 427 to mice bearing BxPC 3 human pancreatic tumor xenografts, PHT 427 inhibited the phosphorylation of both Akt and PDPK1 as well as downstream targets